HIV-1-Infected CD4+ T Cells Facilitate Latent Infection of Resting CD4+ T Cells through Cell-Cell Contact
نویسندگان
چکیده
منابع مشابه
Numerical analysis of fractional order model of HIV-1 infection of CD4+ T-cells
In this article, we present a fractional order HIV-1 infection model of CD4+ T-cell. We analyze the effect of the changing the average number of the viral particle N with initial conditions of the presented model. The Laplace Adomian decomposition method is applying to check the analytical solution of the problem. We obtain the solutions of the fractional order HIV-1 model in the form of infini...
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In this paper we consider a fractional order model of HIV infection of CD4+T cells and we transform this fractional order system of ordinary differential equations to a system of weakly singular integral equations. Afterwards we propose a Nystrom method for solving resulting system, convergence result and order of convergence is obtained by using conditions of existence and uniqueness of solut...
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Highly active antiretroviral therapy (HAART) is able to suppress human immunodeficiency virus type 1 (HIV-1) to undetectable levels in the majority of patients, but eradication has not been achieved because latent viral reservoirs persist, particularly in resting CD4(+) T lymphocytes. It is generally understood that HIV-1 does not efficiently infect resting CD4(+) T cells, and latent infection ...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2018
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2018.07.079